Metabolomic profiling and antidiabetic activity of Callerya speciosa .

Natural product research(2023)

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摘要
is a perennial edible and medicinal plant belonging to the family Fabaceae. This study was to reveal the similarities and differences between phytochemicals in different parts of using a combination of ultra-performance liquid chromatography with quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS/MS), principal component analysis (PCA) and orthogonal projection to latent structures discriminant analysis (OPLS-DA). In addition, the anti-diabetic activity of extracts was explored. A total of 141 compounds were identified and 34 robustly known chemical markers were marked. PCA and heat map analyses revealed that the stems, leaves and pods had similar phytochemical compounds, while compounds in roots and flowers differed from each other and from those in the above ground parts. In addition, extracts of roots and flowers exhibited anti-diabetic activity, which can be applied to the development of anti-diabetic drugs.
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关键词
Callerya speciosa, UPLC-Q-TOF-MS/MS, metabolomic profiling, anti-diabetic activity, bioavailability
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