Relationship Between Dietary Macronutrients Intake and Biological Aging: a Cross-Sectional Analysis of NHANES Data.

This study aimed to investigate the association between macronutrient intake and biological age. Data were collected from 26,381 adults who participated in the United States National Health and Nutrition Examination Survey (NHANES). Two biological ages were estimated using the Klemera-Doubal method (KDM) and PhenoAge algorithms. Biological age acceleration (AA) was computed as the difference between biological age and chronological age. The associations between macronutrient intakes and AA were investigated. After fully adjusting for confounding factors, negative associations were observed between AA and fiber intake (KDM-AA: β – 0.53, 95