Investigating the Cellular Functions of Β-Glucosidases for Synthesis of Lignocellulose-Degrading Enzymes in Trichoderma Reesei

Ai–Ping Pang,Haiyan Wang,Yongsheng Luo,Funing Zhang,Fu–Gen Wu,Zhihua Zhou,Zuhong Lu,Fengming Lin

Engineering Microbiology（2023）

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摘要

•All 10 β-glucosidases function in cellulase production with cel3j being more crucial.•The CEL3J secretion was Golgi-bypassing and regulated by the mTORC1-GRASP55 axis.•The cel3j overexpression changed the cellulase secretion to unconventional mode.

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关键词

β-glucosidase,cel3j,Unconventional secretion pathway,Endoplasmic reticulum,Golgi

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