CD146 promotes malignant progression of breast phyllodes tumor through suppressing DCBLD2 degradation and activating the AKT pathway.

Jiewen Chen,Qingji Xu,Dan Liu,Xun Li,Mingyan Guo,Xuehui Chen,Jianyou Liao,Rong Lei,Wende Li,Hongyan Huang,Phei Er Saw,Erwei Song,Xiyun Yan,Yan Nie

Cancer communications (London, England)（2023）

引用 1|浏览16

暂无评分

摘要

These findings suggested that CD146 served as an efficacious marker for predicting PT malignant progression and showed promise as a prognosis marker and treatment target of breast malignant PTs. The study further unveiled the essential role of the CD146-DCBLD2/PI3K/AKT axis in the malignant progression of PTs.

查看译文

关键词

dcbld2 degradation,malignant progression,tumor

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要