A WGCNA-based cancer-associated fibroblast risk signature in colorectal cancer for prognosis and immunotherapy response.

Yiming Lv,Jinhui Hu,Wenqian Zheng,Lina Shan,Bingjun Bai,Hongbo Zhu,Sheng Dai

Translational cancer research（2023）

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摘要

This novel CAF-related three-gene signature is expected to become a potential prognostic biomarker in CRC and predict chemotherapy and immunotherapy responses. It may be of considerable value for studying the tumor microenvironment in CRC.

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关键词

Colorectal cancer (CRC), cancer-associated fibroblast (CAF), weighted gene co-expression network analysis (WGCNA), prognosis, immune therapy response

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