Molecularly Imprinted Sensor Based on Carboxylated Carbon Nanotubes/keggin-Type Polyoxometalates Nanocomposite for the Detection of Furazolidone

Due to its properties of mutagenic, teratogenic, and carcinogenic, the detection of furazolidone (FZD) in aquaculture is of great importance for food safety and human health. In this study, molecularly imprinted films modified with carboxylated multi-walled carbon nanotube-phosphomolybdic acid composite were used to fabricate an electrochemical sensor for the determination of FZD. The nanocomposites were characterized using infrared spectroscopy, scanning electron microscopy, energy-dispersive X-ray spectroscopy, and X-ray diffraction. The electrochemical characteristics of the modified electrodes were examined using electrochemical impedance spectroscopy, cyclic voltammetry, and differential pulse voltammetry. The sensor exhibited exceptional catalytic performance. The calibration curves were acquired in the concentration range of 6 nmol·L −1 to 0.6 μmol·L −1 , with a limit of detection of 3.38 nmol·L −1 . Additionally, the sensor proved successful in recognizing FZD in shrimp samples with satisfactory recoveries and precision. The method provides a strategy to construct a molecularly imprinted electrochemical sensing platform using nanomaterials, which has great promise in the field of food safety.