48: Device Strategy in Non-Cardiac Procedures

Background: Invasive non-cardiac procedures (NCPs) are often required while patients receive tMCS due to CS. The purpose of this study is to analyze patients listed for OHT, undergoing NCPs with tMCS devices and their safety to undergo transplantation. Methods: Records for patients listed for OHT from January 2015 to January 2023 were reviewed identifying patients receiving tMCS due to CS and performance of NCPs under support. Results: A total of 152 patients were identified as supported by tMCS due to CS, with a total of 246 devices used as therapeutic approach. The cohort was predominantly male, with an average age of 57±12.4 years. Table 1 summarizes all characteristics and outcomes of CS patients under tMCS. Overall, 39% of patients underwent NCPs under tMCS. Figures 1 and 2 summarizes both trajectories of tMCS support towards OHT, and trajectories of tMCS undergoing NCPs. There is a significant difference in the number of performed transplants when single NCPs are conducted with single or multiple tMCS devices (p=0.0277). In the context of NCP performance, there is a significant difference in the number of performed transplants when comparing single to multiple NCPs, regardless of the number of tMCS devices (p=0.0326) (Table 2). Conclusions: This study suggests that NCPs under tMCS are feasible regardless of the type of intervention, or number of support devices. Larger prospective studies are needed to determine a higher power of analysis to determine safety of technique and survival rates.