Enhancing the inhibition of cell proliferation and induction of apoptosis in H22 hepatoma cells through biotransformation of notoginsenoside R1 by Lactiplantibacillus plantarum S165 into 20(S/R)-notoginsenoside R2

Peng-Hui Wang,Yansong Gao,Ge Yang,Yujuan Zhao,Zijian Zhao, Ge Gao, Liang Zhao,Shengyu Li

RSC Advances（2023）

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摘要

The biotransformation method employed yielded 20( S )-notoginsenoside R2 and 20( R )-notoginsenoside R2 from notoginsenoside R1, and the anti-tumor activity of the transformed compound markly improved.

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关键词

h22 hepatoma cells,apoptosis,notoginsenoside r1,cell proliferation,biotransformation

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