Monocytes and T cells incorporated in full skin equivalents to study innate or adaptive immune reactions after burn injury.

Patrick P G Mulder,Marcel Vlig,Anouk Elgersma, Lotte Rozemeijer, Leonore S Mastenbroek,Esther Middelkoop,Irma Joosten,Hans J P M Koenen,Bouke K H L Boekema

Frontiers in immunology（2023）

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摘要

Collectively, this study represents a significant advancement in the development of an immunocompetent human skin model, specifically tailored for investigating burn-induced innate or adaptive immune reactions at the site of burn injury.

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关键词

immune response,cytokines,flow cytometry,immunohistochemistry,macrophages

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