Investigating the impact of linseed supplementation, rich in omega-3 fatty acids, on the expression of immune genes in Beetal Goats
Animal biotechnology(2023)
摘要
The present study investigated the effect of linseed supplementation on serum profiling and differential expression levels of IL-2 and TLR 2 genes involved in the immune system of lactating goats. The study was conducted on 15 lactating Beetal goats for 3 months, which were divided into three groups. Treatment group T-1 was kept as a control group with no linseed supplementation, whereas treatment group T-2 received ground linseed at the rate 10% of concentrate per day per animal, and treatment group T-3 received 20% ground linseed. The concentration of triglycerides, cholesterol and LDL concentration were found to be significantly lower (P < 0.05) in both 10% and 20% linseed supplemented group than the control group. Whereas, HDL concentration in T-2 and T-3 group were found to be significantly higher than the control group. The differential expression of targeted genes comparatively revealed highest relative expression in the group that received 20% linseed supplementation. Although the study did not show a significant effect of linseed supplementation on the expression of TLR-2 and IL-2 genes in goats, it highlights the potential benefits of omega-3 PUFA supplementation on immune system modulation in animals.
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关键词
Beetal goat,IL-2,TLR-2,immune system,cholesterol
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