Design and Characterization of the Detector Readout Electronics Used in PETcoil: an RF-Penetrable TOF-PET Insert for PET/MRI

IEEE Transactions on Radiation and Plasma Medical Sciences(2023)

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摘要
article presents a comprehensive description of the front-end detector readout electronics designed for positron emission tomography (PET) coil, an RF-penetrable TOF-PET insert for PET/MRI. The highly integrated front-end design is based on a mixed ASIC + FPGA approach and incorporates carefully designed power, thermal, and MR compatibility solutions. Experimental results show that the front-end design achieves excellent coincidence time resolution of 238.9 +/- 0.3 ps with real-time TDC bin width calibration and energy resolution of 10.9% +/- 1.1%. The results also indicate good TOF position linearity and clear energy photopeaks. Additionally, the frontend design demonstrates the capability to handle high-count rate applications, with less than 0.005% data loss or corruption observed when the count rate per SiPM channel increased from 3 to 20 kcps. The detector module temperature remained stable at 23.9 degrees C +/- 1.3 degrees C throughout the entire 1-h experiment. These results indicate that this front-end design is feasible for high-sensitivity TOF PET applications.
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关键词
Detectors,Clocks,Magnetic resonance imaging,Field programmable gate arrays,Positron emission tomography,Neuroimaging,Readout electronics,Brain imaging,MR-compatible,readout,RF-penetrable,TOF-positron emission tomography (PET)
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