Glomerular and tubular effects of dapagliflozin, eplerenone and their combination in patients with chronic kidney disease: A post-hoc analysis of the ROTATE-3 study.

Tom T G F Lieverse,Maria J Puchades,Udo D J Mulder,Michele Provenzano,Guido Krenning,Niels Jongs,Simon E Wink,Riemer H J A Slart,Michele Andreucci,Luis D'Marco,Luca De Nicola,Jose L Gorriz,Hiddo J L Heerspink

Diabetes, obesity & metabolism（2023）

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摘要

Dapagliflozin and eplerenone exert different effects on markers of glomerular and tubular function supporting the hypothesis that different mechanistic pathways may account for their kidney protective effects.

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