Dose-dense neoadjuvant chemotherapy before radical surgery in cervical cancer: a retrospective cohort study and systematic literature review.

Giuseppe Caruso,Simone Bruni,Mariateresa Lapresa,Luigi A De Vitis,Gabriella Parma, Valentina Minicucci,Ilaria Betella,Gabriella Schivardi,Fedro Peccatori,Roberta Lazzari,William Cliby,Giovanni Damiano Aletti,Vanna Zanagnolo,Angelo Maggioni,Nicoletta Colombo,Francesco Multinu

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society（2023）

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摘要

Dose-dense neoadjuvant chemotherapy before radical surgery could be a valid strategy to avoid radiotherapy in stage IB1-IIA2 cervical cancer, especially in young patients desiring to preserve overall quality of life. Prospective research is warranted to provide robust, high-quality evidence.

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