Association of Cardiovascular Health With Risk of Incident Depression and Anxiety

•What is the primary question addressed by this study?What is the association between cardiovascular health and incident depression and anxiety?•What is the main finding of this study?In this large prospective cohort study including 115,855 participants from UK Biobank, we found higher cardiovascular health defined by the American Heart Association's Life's Essential 8 score was strongly associated with lower risk of incident depression and anxiety.•What is the meaning of the finding?Our findings indicated cardiovascular health measured by Life's Essential 8 score may be an indicator of potential risk of depression and anxiety.