High-Resolution and Noninvasive Fetal Exome Screening

Harrison Brand, Christopher W. Whelan, Michael Duyzend,John Lemanski,Monica Salani,Stephanie P. Hao,Isaac Wong,Elise Valkanas, Caroline Cusick,Casie Genetti, Lori Dobson, Courtney Studwell, Kathleen Gianforcaro, Louise Wilkins-Haug, Stephanie Guseh,Benjamin Currall, Kathryn Gray,Michael E. Talkowski

NEW ENGLAND JOURNAL OF MEDICINE（2023）

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摘要

Fetal Exome from Maternal Blood Draw The authors describe a noninvasive prenatal screening approach involving a survey of sequence variation across the entire fetal exome using cell-free DNA obtained from a maternal blood draw.

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