Mutation Analysis of KRAS and BRAF in Iranian Colorectal Cancer patients: A Novel Variant in Exon 15 of BRAF.

Bita Hassani,Rasoul Alizadeh,Mansoureh Akouchekian,Fahimeh Safarnezhad Tameshkel,Mohammad Hadi Karbalaie Niya

Asian Pacific journal of cancer prevention : APJCP（2023）

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摘要

We found a novel variant in BRAF gene. The p. Ser616Thr (c.1846T>A) mutation was not previously reported and we conclude that other new mutations can be identified in KRAS and BRAF which may lead to colorectal cancer.

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