Front Cover: Constraining and Modifying Peptides Using Pd‐Mediated Cysteine Allylation (ChemBioChem 13/2023)

ChemBioChem(2023)

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摘要
Pd-mediated cysteine allylation allows to constrain and rigidify peptides by linking two cysteine side chains with a large set of easily available stapling reagents. The staple itself can be further functionalized based on its inherent reactivity thereby allowing construction of a large variety of solid peptides. More information can be found in the Research Article by C. F. W. Becker et al.
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modifying peptides
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