Electrospun hydroxypropyl-β-cyclodextrin nanofibers loaded with anti-inflammatory drugs for potential therapeutic wound dressings

Journal of Molecular Liquids(2024)

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摘要
•New nanofibrous webs of NSAI drugs were fabricated using electrospinning.•Enhanced water-solubility and high thermal stability of NSAI drugs was obtained.•NSAID-HPβCD-IC-NFs exhibited excellent biocompatibility with skin fibroblasts.•NSAID-HPβCD-IC-NFs promoted a rapid rate of wound closure.
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关键词
Non-steroidal anti-inflammatory drugs,2-Hydroxypropyl-β-cyclodextrin,Electrospun nanofibers,In vitro cytotoxic activity,Wound healing
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