Mp32-19 impact on sexual function of endoscopic enucleation versus transurethral resection of the prostate for lower urinary tract symptoms due to benign prostatic hyperplasia: a systematic review and meta-analysis

You have accessJournal of UrologyBenign Prostatic Hyperplasia: Surgical Therapy & New Technology II (MP32)1 Apr 2020MP32-19 IMPACT ON SEXUAL FUNCTION OF ENDOSCOPIC ENUCLEATION VERSUS TRANSURETHRAL RESECTION OF THE PROSTATE FOR LOWER URINARY TRACT SYMPTOMS DUE TO BENIGN PROSTATIC HYPERPLASIA: A SYSTEMATIC REVIEW AND META-ANALYSIS Yuqing Liu*, Jian Lu, Chunlei Xiao, and Lulin Ma Yuqing Liu*Yuqing Liu* More articles by this author , Jian LuJian Lu More articles by this author , Chunlei XiaoChunlei Xiao More articles by this author , and Lulin MaLulin Ma More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000000876.019AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Although the transurethral resection of the prostate (TURP) has been regarded as the gold standard surgical option for lower urinary tract symptoms due to benign prostatic hyperplasia, the endoscopic enucleation of the prostate (EEP) with novel techniques is also recommended. However, whether there are differences on male sexual functions after these two procedures is still controversial. METHODS: We performed this meta-analysis to investigate the impact on erectile function and ejaculation of EEP and TURP, (the protocol of this systematic review was published on www.crd.york.ac.uk/PROSPERO), and to explore the potential superiority between these two approaches. Literature search was conducted on Medline, Embase and the Cochrane library, to obtain all relevant randomized controlled trials published before December 13, 2018. Outcome data were pooled and analyzed with Review Manager 5.3 to compare the International Index of Erectile Function 5 (IIEF-5) scores and retrograde ejaculation rates from short to long term follow-ups. RESULTS: Ten articles with 1435 patients were included. EEP group showed higher IIEF-5 scores than TURP group with mean difference (MD)=1.00, 95% confidence interval (CI): 0.95-1.05 at 48 months and MD=1.08, 95% CI: 1.03-1.13 at ≥60 months, respectively. In subgroup analysis, the holmium laser enucleation of the prostate showed significantly better IIEF scores than TURP group at 48 months (MD=1.00, 95% CI: 0.95-1.05) and ≥72 months (MD=1.08, 95% CI: 1.03-1.13). Additionally, no significant difference in retrograde ejaculation rate was found between EEP and TURP (RR=1.02, 95% CI: 0.85-1.23). CONCLUSIONS: Compared with TURP, EEP may produce a more durable benefit for postoperative preservation of erectile function at long-term stage. The subgroup analyses showed that the advantage of EEP was dominated by HoLEP at long-term stage. In addition, no difference was evident regarding the rate of retrograde ejaculation between EEP and TURP. Source of Funding: Supported by Key Program on Clinical Subject of Peking University Third Hospital (BYSY2016020) © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 203Issue Supplement 4April 2020Page: e492-e492 Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.MetricsAuthor Information Yuqing Liu* More articles by this author Jian Lu More articles by this author Chunlei Xiao More articles by this author Lulin Ma More articles by this author Expand All Advertisement PDF downloadLoading ...