Genetic characterization of B-cell prolymphocytic leukemia: a prognostic model involving MYC and TP53 Élise Chapiro , Élodie Pramil , M’Boyba Diop , Damien Roos‐Weil , Clémentine Dillard , Clémentine Gabillaud , Karim Maloum , Catherine Settegrana , Lucile Baseggio , Jean‐François Lesesve , Mélanie Yon , Ludovic Jondreville , Claude Lesty , Frédéric Davi , Magali Le Garff‐Tavernier , Nathalie Droin , Philippe Dessen , Caroline Algrin , Véronique Leblond , Jean Gabarre , Simon Bouzy , Virginie Éclache , Baptiste Gaillard , Evelyne Callet‐Bauchu , Marc Müller , Christine Lefebvre , Nathalie Nadal , Antoine Ittel , Stéphanie Struski , Marie‐Agnès Collonge‐Rame , Benoît Quilichini , Sandra Fert‐Ferrer , Nathalie Auger , Isabelle Radford–Weiss , Lena Wagner , Sebastian Scheinost , Thorsten Zenz , Santos A. Susin , Olivier A. Bernard , Florence Nguyen‐Khac Blood(2019)
摘要
Key Points B-PLL is tightly linked to MYC aberrations (translocation or gain) and 17p (TP53) deletion. Cases of B-PLL with MYC aberration and 17p (TP53) deletion have the worst prognosis.
更多 查看译文
关键词
leukemia, genetic characterization, myc, b-cell
AI 理解论文
溯源树
样例