Effect of Eplontersen on Cardiac Structure and Function in Patients With Hereditary Transthyretin Amyloidosis

Ahmad Masri,Mathew S. Maurer,Brian L. Claggett,Ian Kulac,Marcia Waddington Cruz,Isabel Conceição,Markus Weiler,John L. Berk,Morie Gertz,Julian D. Gillmore, Stephen Rush,Jersey Chen,Wunan Zhou,Jesse Kwoh, Jason M. Duran,Sotirios Tsimikas,Scott D. Solomon

Journal of Cardiac Failure（2023）

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摘要

vATTR, variant transthyretin; LV, left ventricle; E/e′, ratio of early diastolic mitral inflow velocity to early diastolic mitral annulus velocity; NT-proBNP, N-terminal prohormone of brain natriuretic peptide.Image, graphical abstract

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关键词

Amyloidosis,eplontersen,transthyretin,echo,clinical trial,polyneuropathy

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