Reviewing the role of dietary lipids in coronary heart disease

It has been shown that coronary heart disease (CHD) is related to high serum total cholesterol (TC) levels. In all the urban population compared with the rural population is showed a rise of serum TC. This is reflected in the trend of CHD morbidity and mortality as well. In spite of a declining trend in serum TC level, CHD morbidity and mortality are still high year after year. In general, there is still a rising trend in serum TC level and in CHD mortality in many countries. However it may be controlled and managed. This may be attributed to a better control of other CHD risk factors such as hypertension and smoking. More than a century of laboratory and human findings cholesterol levels with a propensity to develop atherosclerosis. Low-density lipoprotein (LDL) is the major atherogenic lipoprotein, and numerous clinical trials have shown the efficacy of lowering LDL-cholesterol (LDL-C) for reducing CHD 127 risk. The rising trend in serum TC level remains a cause for concern, as this will emerge as a major problem for CHD morbidity and mortality in the future.