Supplementary Information from Mouse Homolog of the Human TP53 R337H Mutation Reveals Its Role in Tumorigenesis
openalex(2023)
摘要
This Supplemental Information file contains the Materials and Methods for the supplementary tables and figures merged into this same file. These are Tables 1-3 which show primer sequences, observed genotypes and gender of p53 R334H mouse crossings, and incidence of adrenal abnormalities; and Figures S1-S9 which provide additional data on mouse phenotype, DEN metabolism, tumor LOH, DNA damage time course, oncogene-induced senescence in MEFs, p53 expression levels, and further oligomerization studies.
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关键词
r337h mutation,tumorigenesis,mouse homolog
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