Augmentation of Omicron BA.1 pathogenicity in hamsters using intratracheal inoculation

Julia R. Port,Claude Kwe Yinda, Claire Ruckel,Jonathan E. Schulz,Brian J. Smith,Carl I. Shaia,Vincent J. Munster

Research Square (Research Square)（2024）

引用 0|浏览5

暂无评分

摘要

The Omicron BA.1 variant of SARS-CoV-2 displays an attenuated phenotype in the Syrian hamster after intranasal inoculation. This is characterized by reduced viral replication and lung pathology in the lower respiratory tract. Here, we report that intratracheal inoculation with Omicron BA.1 recovers the lower respiratory tract replication and pathogenicity as observed with other lineages.

查看译文

关键词

omicron pathogenicity,intratracheal inoculation,hamsters

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要