The role of NOTCH-signaling in mediating therapy resistance in rectal cancer

G. Chelik,Melanie Spitzner, Aisha L. Siebert,B. Michael Ghadimi,Günter Schneider,Jürgen Wienands,Marian Grade

Zeitschrift Fur Gastroenterologie（2023）

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摘要

Background Rectal cancer is associated with high morbidity and mortality rates affecting both men and women worldwide. In this context, resistance to chemoradiotherapy remains a major clinical dilemma.

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关键词

rectal cancer,therapy resistance,notch-signaling

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