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Influence of Salt Intake on Segmental Lesions of Patients with Ischaemic Heart Disease in Sri Lanka: A Cross-sectional Study

Harishchandra Amadoru,Rajitha Yasela De Silva, Kariyawasam Don Nandasiri Weerasinghe, Manjriker Gunaratne,Pasyodun Koralage Buddhika Mahesh, Sumudu Prasangi Rupasinghe Siriwardena, Pradeep Gamage, Kaluwelle Mudalige Vishva Randhara Alles,Upuli Perera, Ravikaran Anthonypillai, Vasana Suriyaraachchi, Kankanamge Rasika Nuwan Wijesiri, Sajeewanie Nisansala Liyanage, Arunie Kokila Malwatta, Jayasekara Liyanaarachchige Prasanna Jayasekara,Renuka Jayatissa, A.D. Kapuruge

Journal of Asian Pacific Society of Cardiology(2023)

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摘要
Background: Sodium assists in maintaining body fluid balance. Excess sodium intake increases the risk of ischaemic heart disease (IHD) adding to global and local mortality due to non-communicable diseases. Aim: To determine the salt intake levels of patients having coronary artery bypass grafting (CABG) and to explain the relationship between salt consumption and atheroma development. This study used an adapted cross-sectional design with 233 patients admitted to Sri Jayewardenepura General Hospital with acute heart diseases. Method: Demographic and lifestyle-related data, medical history and food intake data were collected. Salt intake was calculated based on the consumption of salt used per month at household level, salt added to food – including in restaurants. Salt content was determined using web-based applications and food tables. Multivariate logistic regression was used to identify variables significantly associated with IHD. Results: In this study, the daily intake of sodium per person was 6,176 mg. This was much higher than WHO’s recommended level of 2,000 mg/day, demonstrating a significant relationship between segmental lesions and sodium intake (p<0.01). The multivariate binary logistic model demonstrated that high salt intake (OR 8.54; 95% CI [4.545–16.734]) and the presence of diabetes (OR 2.23; 95% CI [1.206–4.238]), contributed to the high number of segmental lesions (p<0.01). Conclusion: A high daily intake of sodium increases the risk of atheroma formation in more coronary segments, regardless of age, sex, several known disease conditions and risk factors.
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关键词
ischaemic heart disease,salt intake,cross-sectional
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