A rare case of cemento-ossifying fibroma in a 13-year-old boy with Crouzon syndrome with acanthosis nigricans

Cemento-ossifying fibroma (COF) is a fibro-osseous lesion of the jaw. It was defined as a benign mesenchymal odontogenic tumor according to the World Health Organization (WHO) histological classification of 2017. COF is a relatively rare tumor that generally occurs in the mandibular molar region of adult women. Herein, we report a case of COF that occurred symmetrically in the bilateral anterior mandibular regions of a child. The patient was a 13-year-old boy who had Crouzon syndrome. He was referred to our clinic because radiolucent lesions were detected in the bilateral anterior mandibular regions on panoramic radiography. Computed tomography revealed lesions in the bilateral mandibular anterior regions. The lesions were completely removed, and histopathological examinations were performed, which confirmed COF in bilateral lesions. There was no evidence of recurrence at the 2-year postoperative follow-up.