Big Data and Artificial Intelligence for Exploring the Role of Genetic Risk. Family History of Cancer and Lung Cancer. Results from CLARIFY

Lung cancer is a disease of multifactorial origin linked to extrinsic or modifiable environmental factors, tobacco, radon and others. There are other intrinsic or non-modifiable factors; age, sex, family and personal history (previous respiratory diseases, and genetic susceptibility). In the assessment of genetic susceptibility, family history of cancer has been used as a surrogate for genetic risk.