Cu-Catalyzed Convenient Synthesis of 2-Trifluoromethyl Benzimidazoles via Cyclization of o-Phenylenediamines with Hexafluoroacetylacetone

Changjiu Xia,Xiaoyu Zhou, Hailong Liu,Sheng Zhang, Mengying Bao

Organic and Biomolecular Chemistry(2023)

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摘要
An efficient and convenient method for the synthesis of 2-trifluoromethyl benzimidazoles is described in this paper. The cyclization reaction of various o-phenylenediamines with hexafluoroacetylacetone proceeded smoothly in the presence of...
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