Effect of tween 80 on the stability and conformation of telomeric g-quadruplex dna
CHEMISTRY & CHEMICAL TECHNOLOGY(2023)
摘要
G-quadruplex DNA is formed in telomer. It inhibits telomerase enzyme which is found active in more than 85 % of cancer cells. In this work, the effect of Tween 80 on telomeric G-quadruplex DNA, AGGG(TTAGGG)3 was studied using circular dichroism spectroscopic technique. The obtained results showed that using Tween 80 with telomeric quadruplex is safe up to less than 1.0 %.
更多查看译文
关键词
telomere,quadruplex,Tween 80,circular dichroism,conformation
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要