An open-label randomised-controlled trial of azathioprine vs. mycophenolate mofetil for the induction of remission in treatment-naive autoimmune hepatitis

Journal of Hepatology(2023)

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摘要
•Limited efficacy and tolerability of standard prednisolone and azathioprine combination therapy in autoimmune hepatitis.•Mycophenolate mofetil combined with prednisolone is effective as first-line therapy for achieving biochemical remission.•Mycophenolate mofetil has a more favourable tolerability profile than azathioprine.
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关键词
autoimmune hepatitis,azathioprine,mycophenolate mofetil,first-line treatment,induction therapy,randomised-controlled trial,remission,biochemical remission,phase IV trial
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