Pulsed electromagnetic field stimulation enhances neurite outgrowth in neural cells and modulates inflammation in macrophages

Francesco Fontana,Andrea Cafarelli,Francesco Iacoponi, Soria Gasparini, Tiziano Pratellesi,Abigail N． Koppes,Leonardo Ricotti

Engineered Regeneration（2024）

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摘要

•We applied pulsed electromagnetic field (PEMF) stimulation on nerve cells.•We screened different parameters and found the optimal ones to improve neurite outgrowth.•The same parameters had anti-inflammatory effects on macrophages, opening venues for nerve regeneration after injuries.

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关键词

Nerve regeneration,Biophysical stimulation,Pulsed electromagnetic fields (PEMF),Neurite outgrowth,Anti-inflammatory,Peripheral nerve injuries

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