Optimising chemo-enzymatic separation of polyester cellulose blends

•Increasing textile waste generation has risen European Union to implement regulations and strategies.•Chemo-enzymatic treatment of blended textiles enabled selective hydrolysis and removal of cellulose allowing polyester recovery.•Precise condition adjustment is crucial to avoid polyester damage and ensure complete cellulose removal.•Optimized conditions can transform the textile industry from linear to circular, reducing the amount of textile waste.•Industrial implementation realises a sustainable textile biorefinery concept.