Prognostic variables predict clinical outcome after decompressive craniectomy: A single institute experience; A retrospective study

Ebtesam Abdulla,Krishna Das,Kannan Sridharan, Mohammed Waheed, Fatima Abdulla,Joseph Ravindra, Harleen Luther,Andrew Awuah Wireko

MEDICINE(2024)

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摘要
Decompressive craniectomy (DC) is a well-established neurosurgical intervention in patients with high intracranial pressure who fail to respond to medical treatment. Data on predictive factors for functional outcomes in patients with DC who have malignant middle cerebral artery (MCA) infarction as opposed to intracranial hemorrhage (ICH) are scarce. Eighty-four patients who underwent DC treatment for ICH and malignant MCA infarction were examined. All patients underwent surgery in the Bahrain Salmaniya Medical Complex Neurosurgery Unit between January 2017 and June 2021. To determine whether any of these demonstrated a link to the functional outcome, radiographic factors were compared with clinical data. The postsurgical midline shift (MLS) (ICH group) showed the strongest correlation (rho = 0.434; P = .006), as in the MCA infarction group as well (rho = 0.46; P = .005). Further analyses using binary logistic regression with postsurgical basal cistern status and increment MLS, and it was observed to be statistically significant (odds ratios: 0.067, 95% CI: 0.007, 0.67; P = .021). The initial Glasgow coma scale, postsurgical MLS, basal cistern status, and increment are Measurable variables that can be used to predict outcomes in the groups with ICH and MCA infarction.
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关键词
decompressive hemicraniectomy,intracranial bleeding,intracranial pressure,middle cerebral artery infarction
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