Generation of induced pluripotent stem cell line from a patient suffering from arterial calcification due to deficiency of CD73 (ACDC)

Dipti Tripathi,Amit Manhas,Chikage Noishiki,David Wu,Shaunak Adkar,Karim Sallam,Eri Fukaya, Nicholas J. Leeper,Nazish Sayed

Stem Cell Research（2024）

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摘要

•A iPSC line was generated from Arterial calcification due to deficiency of CD73 patient.•This iPSC line carries mutation in the NT5E gene (missense).•This iPSC line showed a normal karyotype and high pluripotency.•This iPSC line can provide a tool for modeling ACDC in vitro.

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关键词

Arterial calcification due to deficiency of CD73,Induced pluripotent stem cells,NT5E

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