Alpha-santalol, a derivative of sandalwood oil prevents development of prostate cancer in TRAMP mice

Ajay Bommareddy, John Oberlin, Kaitlyn Blankenhorn, Sarah Hughes,Erica Mabry,Aaron Knopp,Adam VanWert,Chandradhar Dwivedi, Isaiah Pinkerton, Linda Gutierrez

Phytomedicine Plus（2024）

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摘要

•Alpha-santalol administration prevents prostate cancer development in TRAMP mice.•Expression of normal tissue is higher alpha-santalol group compared to control.•Alpha-santalol treatment induces apoptosis and reduces cell proliferation.

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关键词

Natural products,Alpha-santalol,Prostate cancer,Apoptosis,Survivin,Transgenic mice

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