Intravenous lipid emulsion for a life-threatening prothipendyl intoxication
BMJ CASE REPORTS(2024)
摘要
Prothipendyl, a lipophilic neuroleptic drug, requires a careful dosage regimen due to its potential side effects, including life-threatening arrhythmias.This report outlines a case of severe prothipendyl intoxication, its management and the successful utilisation of Intralipid, an intravenous lipid emulsion, in treating ventricular arrhythmia postmassive prothipendyl ingestion. Additionally, the mechanism of action of Intralipid and the rebound concentration of the lipophilic drug in such scenarios are discussed.
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关键词
Drugs and medicines,Cardiovascular system,Adult intensive care,Drug interactions,Toxicology
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