Valorisation of fruit waste for harnessing the bioactive compounds and its therapeutic application

Background: Fruit processing by-products, especially pomace, peels, rinds, and seeds, are underused and mostly discarded as waste. Such biowastes are rich in beneficial bioactive like carotenoids, enzymes, polyphenols, oils, vitamins, and other biomolecules possessing various health-promoting properties. Therefore, these bioactive substances from agro-waste can be recovered and recycled to create functional food items that may gain popularity. The opportunity to generate additional revenue for the industrial sector can be provided by the sustainable utilization of agri-food wastes and by-products to produce indispensable biomolecules and valueadded products. Scope and approach: This review combines a case study methodology with a selective analysis of the peerreviewed research and review articles. The data has been collected from various research platforms, including Google Scholar and PubMed. Articles have been thoroughly studied and examined in the last five years to give the collated form of wholesome information. In addition, recent progress and possible therapeutic perspectives have been discussed for fruit waste-based bioactivity. Key findings and conclusions: Bioactives prevent diabetes, overweight, Alzheimer's, and Parkinson's diseases, and microbial inhibition. Due to broad therapeutic benefits and possible specialized uses, bioactive garners are increasing interest in their recovery from biowastes such as fruit-derived wastes. This review explores fruit biowaste-based bioactives and their bioavailability and potential therapeutic uses. This study's finding suggested that efficient biowaste/by-product valorisation can minimize environmental burdens and generate valuable bioactive, which have broad beneficial applications. Future exploring strategies for efficiently recovering fruit waste bioactives and their uses via a sustainable development approach can be more anticipated.