The Vulnerable Elders Survey-13 scale is superior to the simplified Pulmonary Embolism Score Index in predicting 3-month postdischarge mortality in elderly survivors of acute pulmonary embolism

Anna M. Imiela, Elzbieta Kozak-Szkopek, Monika Szymanska, Katarzyna Wdowiak,Olga Dzikowska-Diduch, Aleksandra Zuk-Lapan, Andrzej Pruszczyk, Izabella Bukalska, Karolina Niewczas,Michal Machowski, Aisha Ou-Pokrzewinska,Piotr Pruszczyk

POLISH ARCHIVES OF INTERNAL MEDICINE-POLSKIE ARCHIWUM MEDYCYNY WEWNETRZNEJ(2024)

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摘要
INTRODUCTION Acute pulmonary embolism (APE) is the most serious manifestation of venous thromboembolism. The simplified Pulmonary Embolism Severity Index (sPESI) is employed for prediction of 30 -day mortality in APE. The Vulnerable Elders Survey (VES-13) is used to identify participants at a risk of health impairment. OBJECTIVES We aimed to compare the VES-13 and sPESI scales for prediction of 3 -month mortality in elderly patients hospitalized for APE. PATIENTS AND METHODS All patients with APE were managed according to the European Society of Cardiology (ESC) guidelines and followed up for at least 3 months after discharge. Clinical evaluation of all patients involved the Charlson Comorbidity Index (CCI) and biochemical tests. The patients with VES-13 score equal to or above 3 (VES-13>_3) were evaluated with comprehensive geriatric assessment (CGA). RESULTS A total of 164 patients met the inclusion criteria. There were significantly fewer men in the VES-13>_3 than the VES-13<3 group (34% vs 54.5%; P <0.01). The patients in the VES-13>_ 3 group had lower median (interquartile range [IQR]) body mass index and higher sPESI score than those in the VES-13<3 group (25.6 [21.8-28.4] kg/m(2) vs 28 [25.3-31] kg/m2; P = 0.001 and 2 [1-2] points vs 1 [0-1] point; P <0.001, respectively). There were no differences in APE severity according to the ESC stratification and CCI. Logistic regression analysis identified the VES-13 score as a significant independent risk factor for 3 -month mortality. CONCLUSIONS The VES-13 score is a better tool than sPESI for predicting 3 -month mortality. Geriatric survivors of APE characterized with VES-13>_ 3 points should be closely monitored after discharge. The Norton Scale Score in a combination with the VES-13 may be useful in predicting 3 -month mortality among numerous tests used in the CGA.
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关键词
comprehensive geriatric assessment,pulmonary embolism,simplified Pulmonary Embolism Score Index,Vulnerable Elders Survey-13 scale
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