Serologic Response to Vaccine for COVID-19 in Patients with Hematologic Malignancy: A Prospective Cohort Study

Alexandra Hillyer, Anthony Quint, Artin Ghassemian, Nicolette Joh-Carnella,Michael J. Knauer, Danny Dawd,Alejandro Lazo-Langner,Joy Mangel,Selay Lam,Husam Abdoh,Anargyros Xenocostas,Uday Deotare,Lalit Saini, Cheryl Foster,Martha Louzada,Jenny Ho, Ian Chin Yee,Chai W. Phua

Clinical Lymphoma Myeloma and Leukemia（2024）

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摘要

•Patients with hematologic malignancies have lower immune response to vaccination•Active cancer treatment is associated with lower post-COVID vaccination titers•Three COVID-19 vaccines mitigated poor immune response in patients on treatment•Anti-CD20 inhibitor patients had poor vaccination response after three vaccines

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COVID-19,hematological malignancy,vaccination response,anti-CD20 therapy

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