Cognitive dysfunction in early experimental non-alcoholic fatty liver disease is associated with systemic and neuroinflammation

Kristoffer Kjærgaard,Anne Catrine Daugaard Mikkelsen,Anne M. Landau,Peter Lykke Eriksen,Stephen Hamilton-Dutoit,Nils Erik Magnusson,Majken Borup Thomsen,Fenghua Chen,Hendrik Vilstrup,Rajeshwar Prosad Mookerjee,Cecilie Bay-Richter,Karen Louise Thomsen

JHEP Reports（2023）

引用 0|浏览5

暂无评分

摘要

•This study provided evidence for memory loss and altered behaviour in a NAFLD animal model•Cognitive dysfunction was associated with systemic and neuroinflammation•Diminished synaptic density was observed in the prefrontal cortex•The study suggests a pathophysiological link between NAFLD and cognitive dysfunction

查看译文

关键词

Non-alcoholic fatty liver disease,Non-alcoholic steatohepatitis,Liver-brain axis,hepatic encephalopathy,Neuroscience,Cognitive dysfunction,Neuroinflammation,Systemic inflammation

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要