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Smart Ph Sensing: A Self-Sensitivity Programmable Platform with Multi-Functional Charge-Trap-Flash ISFET Technology

Sensors(2024)SCI 3区

Kwangwoon Univ

Cited 0|Views1
Abstract
This study presents a novel pH sensor platform utilizing charge-trap-flash-type metal oxide semiconductor field-effect transistors (CTF-type MOSFETs) for enhanced sensitivity and self-amplification. Traditional ion-sensitive field-effect transistors (ISFETs) face challenges in commercialization due to low sensitivity at room temperature, known as the Nernst limit. To overcome this limitation, we explore resistive coupling effects and CTF-type MOSFETs, allowing for flexible adjustment of the amplification ratio. The platform adopts a unique approach, employing CTF-type MOSFETs as both transducers and resistors, ensuring efficient sensitivity control. An extended-gate (EG) structure is implemented to enhance cost-effectiveness and increase the overall lifespan of the sensor platform by preventing direct contact between analytes and the transducer. The proposed pH sensor platform demonstrates effective sensitivity control at various amplification ratios. Stability and reliability are validated by investigating non-ideal effects, including hysteresis and drift. The CTF-type MOSFETs’ electrical characteristics, energy band diagrams, and programmable resistance modulation are thoroughly characterized. The results showcase remarkable stability, even under prolonged and repetitive operations, indicating the platform’s potential for accurate pH detection in diverse environments. This study contributes a robust and stable alternative for detecting micro-potential analytes, with promising applications in health management and point-of-care settings.
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pH sensor platform,ion-sensitive field-effect transistor (ISFET),charge trap flash (CTF),self-sensitivity programmability,resistance coupling effects,sensitivity control
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要点】:本研究提出了一种基于 charge-trap-flash 型 MOSFET 技术的自灵敏编程智能 pH 传感平台,通过 resistive coupling 效应和 CTF-type MOSFETs 的灵活放大比调整,克服了传统 ISFETs 灵敏度低的问题。

方法】:采用 charge-trap-flash-type MOSFETs 作为传感器和电阻器,通过 extended-gate (EG) 结构增强成本效益和平台寿命。

实验】:通过研究非理想效应(包括迟滞和漂移)验证了平台的稳定性和可靠性,并通过长期反复操作展示了 CTF-type MOSFETs 的稳定性。在各种放大比下,该 pH 传感平台能有效控制灵敏度,展现了在健康管理和 point-of-care 设置中准确检测微小电位分析物的潜力。