Study on the Growth and Regulation of Large-Particle Sr(OH)28H2O Crystals with Process Analytical Technology
CRYSTALS(2024)
摘要
Sr(OH)(2) is an indispensable strontium compound extensively harnessed in sugar refining, strontium lubricating wax formulation, and polymer plastic stabilization. Sr(OH)(2)8H(2)O is the prevalent hydrate form of Sr(OH)(2). Deprived of moisture via vacuum drying, Sr(OH)(2) can be procured from Sr(OH)(2)8H(2)O. Sr(OH)(2)8H(2)O particles with larger sizes exhibit impressive attributes such as facile solid-liquid divergence, elevated product purity, expedient drying, and resilience to agglomeration, which have garnered significant interest. Given the superior quality of the product and the dependability of the process, process analytical technology (PAT) has been extensively employed in the pharmaceutical sector, rendering it feasible to employ PAT to fabricate large-particle Sr(OH)(2)8H(2)O crystals. This study utilizes industrial SrCO3 to prepare high-purity Sr(OH)(2)8H(2)O with a purity of over 99.5%. The growth process of single crystals was observed using a hot-stage microscope, and the growth process of large-particle Sr(OH)(2)8H(2)O was optimized and regulated online using PAT. The optimal process conditions were optimized, and large-particle Sr(OH)(2)8H(2)O crystals were obtained by adding crystal seeds. On this basis, we proposed a seed control mechanism for Sr(OH)(2)8H(2)O.
更多查看译文
关键词
Sr(OH)(2)<middle dot>8H(2)O,process analytical technology,crystal growth,seed control
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要