Transmission Patterns of Norovirus From Infected Children to Household Members in Len, Nicaragua

Norovirus is a common and highly transmissible gastrointestinal pathogen. Among 34 Nicaraguan households with a norovirus-infected child, 48% experienced norovirus transmission within 1 week, infecting 18% of household members; GII norovirus was more commonly transmitted than GI. Pediatric norovirus vaccines could prevent both index cases and transmission to close contacts. A study of young children with norovirus infection in Nicaragua found that 48% of households experienced norovirus transmission within 1 week (attack rate 18%). Pediatric norovirus vaccination has the potential to reduce the disease burden of norovirus in families.