Advanced and personalized healthcare through integrated wearable sensors (versatile)

Due to people's hectic and intense working schedules, health as a priority is often pushed to the sidelines. This is more problematic for people with some health conditions, which require regular monitoring of vitals. Therefore, the development of smart diagnostics is a clinical challenge towards which, a lot of research is being carried out. This primarily includes the development of wearable sensors. These sensors can be worn by individuals for the monitoring of various biomarkers in different bio-fluids. Primary research is being carried out to make them sensitive, reliable, robust, and non/minimally invasive. Since the intended wearable sensor is to be used for continuous monitoring of the individuals, all the components required for the sensing must be on the same platform. This generally includes the sensing platform, microfluidic channels, and its electronic or optical components. The goal of the current review is to highlight the state-of-the-art integrated wearable sensors, describing their important components, methods of manufacturing, and applications of these sensors and discuss the challenges being faced while designing and scaling up these sensors. The contents of this review will help design and develop novel integrated wearable sensors that are expected to revolutionize the field of personalized healthcare. Applications of integrated wearable sensors for the monitoring of human vital signs and clinically relevant biomarkers.