Potentially Inappropriate Medication Use among Older Adults with Lower-Limb Loss.

Objective: The aim of this study was to evaluate the prevalence of, and explore factors related to, prescription of potentially inappropriate medications (PIMs) among older adults with lower -limb loss (LLL). Methods: This was a secondary analysis of a cross-sectional dataset collected through an interdisciplinary limb loss clinic between September 2013 and November 2022. Self -report medication lists were reviewed during in -clinic face-to-face interviews and compared to the American Geriatrics Society Beers Criteria corresponding to the patient's evaluation year. Results: Of 82 participants (72.9 6.6 years -old; 78.0 % male), n = 41 (50.0 %) reported using one or more PIM. PIM prescription was significantly associated with presence of phantom limb pain, history of upper gastrointestinal issues, and a greater number of medications. Discussion: Polypharmacy and PIM use are common among older adults with LLL. Greater attention should be paid to medications post -amputation, especially pain management medications, to minimize potential adverse side -effects. (c) 2024 Elsevier Inc. All rights reserved.