Florisil As an Efficient Reagent for Deprotection of Tert-Butyl Carbamates, Carbonates and Esters

Florisil (magnesium polysilicate) is an efficient and eco-friendly reagent for the deprotection of tert-butyl carbamates, carbonates, and ethers. Moderate to excellent yields could be achieved in the presence of other acid-sensitive groups. The separation of products is easy, and Florisil can be recycled several times without observing a decrease in yields.