Transient but not chronic hyperglycemia accelerates ocular glymphatic transport

Fluids and Barriers of the CNS(2024)

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摘要
Glymphatic transport is vital for the physiological homeostasis of the retina and optic nerve. Pathological alterations of ocular glymphatic fluid transport and enlarged perivascular spaces have been described in glaucomatous mice. It remains to be established how diabetic retinopathy, which impairs vision in about 50
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关键词
Perivascular spaces,Ocular glymphatic system,Diabetes,Cerebrospinal fluid,Retina,Retinal ganglion cells,Glial lamina,electron microscopy,Magnetic resonance imaging
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