Engineering of halohydrin dehalogenases for the regio- and stereoselective synthesis of (S)-4-aryl-2-oxazolidinones

Jinsong Song, Chuanhua Zhou,Xi Chen,Yang Gu,Feng Xue,Qiaqing Wu,Dunming Zhu

Catalysis Science & Technology(2024)

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摘要
Cyanate-mediated epoxide ring-opening by halohydrin dehalogenases (HHDHs) is a promising method for the synthesis of important optically pure 2-oxazolidinones.
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