Brain Tumor Surgery Utilizing Second Window Indocyanine Green

Gadolinium enhancement of brain tumors on preoperative MRI scans defines the location of great majority of brain tumors prior to craniotomy. The method of dye accumulation is considered to be nonspecific. In a similar manner, we have administered high dose indocyanine green to patients undergoing craniotomy for brain tumor surgical resection. Optical imaging in a delayed fashion demonstrates indocyanine green retention within the tumor with excellent tumor to background signal. This technique -- Second Window ICG -- can provide surgical benefit with respect to early localization.